Are the genes coding for one antibody entirely dfferent from those coding for a different antibody? Explain?

I know gene coding for one antibody is different from another antibody, but the part I am stuck on is are they entirely different?

Are the genes coding for one antibody entirely dfferent from those coding for a different antibody? Explain?
Been a while since immunology, I'll try my best. There are two types of region on an antibody, a constant region and a variable region. The genes coding for the constant region or invariant but the genes coding for this variable region undergo a process known as somatic hypermutation. It is difficult to explain succinctly so know that the genes for the variable segment are arranged into what we call V, D, and J segment. There are multiple V, J, and D segments in the gene for the variable region and their different arrangements into a coding unit account for the majority of antibody diversity.
Reply:They would not be entirely different, as say if 2 diseases cause a severe cough, but one causes a rash whereas the other doesn't, the 'coding' for the cough would pretty much be the same, and the rest would probably be different.





Hope that helps :)
Reply:first, genes for immunonoglubulin consist of several parts which are combined in certain order during transcription and splicing. That's how different combinations for different antibodies are created in the first place. Second, parts of those genes have extremely high rate of mutations - so called hypervariable regions. That's how quite a number of antibodies with different specificities is evolved. So, you cannot say that genes are really different, but they produce different antibodies
Reply:I was just wondering if you were working in Anatomy and Physiology homework too, because the question is word for word what is listed as a question on my homework tonight, which I was looking up too, lol...and there is was on this page! Thank you to those who explained the answer!

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